User profiles for A. Santoni

Antonino Santoni

ENEA
Verified email at enea.it
Cited by 2408

Neutrophil diversity and plasticity in tumour progression and therapy

S Jaillon, A Ponzetta, D Di Mitri, A Santoni… - Nature Reviews …, 2020 - nature.com
Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

[HTML][HTML] The senescence-associated secretory phenotype (SASP) in the challenging future of cancer therapy and age-related diseases

L Cuollo, F Antonangeli, A Santoni, A Soriani - Biology, 2020 - mdpi.com
Simple Summary A fundamental feature of cellular senescence is the emergence of the
Senescence-Associated Secretory Phenotype (SASP), which represents a considerable source …

[HTML][HTML] Regulation of PD-L1 Expression by NF-κB in Cancer

…, A Natalini, MC Garassino, A Sica, A Santoni… - Frontiers in …, 2020 - frontiersin.org
Immune checkpoints are inhibitory receptor/ligand pairs regulating immunity that are exploited
as key targets of anti-cancer therapy. Although the PD-1/PD-L1 pair is one of the most …

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

…, MR Rippo, M Azuma, LL Lanier, A Santoni… - The Journal of …, 1994 - rupress.org
Intracellular pathways leading from membrane receptor engagement to apoptotic cell death
are still poorly characterized. We investigated the intracellular signaling generated after …

Intel virtualization technology

R Uhlig, G Neiger, D Rodgers, AL Santoni… - Computer, 2005 - ieeexplore.ieee.org
A virtualized system includes a new layer of software, the virtual machine monitor. The VMM's
principal role is to arbitrate accesses to the underlying physical host platform's resources …

Cutting edge: the chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells

…, D Robinson, M Rocchi, A Santoni… - The Journal of …, 1998 - journals.aai.org
In this paper we report on the cloning and characterization of mouse CCR8. Like its human
homologue, it is predominantly expressed in the thymus. In the periphery, murine CCR8 …

ATM-ATR–dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is …

…, A Guarini, R Foa, A Santoni - Blood, The Journal …, 2009 - ashpublications.org
There is much evidence to support a role for natural killer (NK) cells in controlling the
progression of multiple myeloma (MM), a malignancy characterized by an abnormal plasma cell …

Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK-cell …

…, M Cippitelli, M Piccoli, L Frati, A Santoni - Blood, The Journal …, 2007 - ashpublications.org
Recent evidence indicates that natural killer (NK) cells can negatively regulate T-cell
responses, but the mechanisms behind this phenomenon as a consequence of NK–T-cell …

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury

…, F Martin, M Gentile, A Santoni… - Proceedings of the …, 2004 - National Acad Sciences
The chemokine CXC ligand 8 (CXCL8)/IL-8 and related agonists recruit and activate
polymorphonuclear cells by binding the CXC chemokine receptor 1 (CXCR1) and CXCR2. Here we …

Tumor necrosis factor alters synaptic transmission in rat hippocampal slices

…, F Grassi, P Tarroni, G Palmieri, A Santoni… - Neuroscience …, 1992 - Elsevier
The effects of human recombinant tumor necrosis factor (TNF-α) on the synaptic transmission
were studied in rat hippocampal slices by using extracellular field potential recordings. …