Features of apoptotic cells measured by flow cytometry
Z Darzynkiewicz, S Bruno, G Del Bino, W Gorczyca… - Cytometry, 1992 - Wiley Online Library
The present review describes several methods to characterize and differentiate between
two different mechanisms of cell death, apoptosis and necrosis. Most of these methods were …
two different mechanisms of cell death, apoptosis and necrosis. Most of these methods were …
[HTML][HTML] Exosomes/microvesicles as a mechanism of cell-to-cell communication
Microvesicles (MVs) are circular fragments of membrane released from the endosomal
compartment as exosomes or shed from the surface membranes of most cell types. An increasing …
compartment as exosomes or shed from the surface membranes of most cell types. An increasing …
Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications
Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are transiting
rapidly towards clinical applications. However, discrepancies and controversies about …
rapidly towards clinical applications. However, discrepancies and controversies about …
Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study
…, H Ball, V Bradley-Barker, Z Brown, S Bruno… - The Lancet …, 2020 - thelancet.com
Background Concerns regarding potential neurological complications of COVID-19 are being
increasingly reported, primarily in small series. Larger studies have been limited by both …
increasingly reported, primarily in small series. Larger studies have been limited by both …
[HTML][HTML] Boceprevir for untreated chronic HCV genotype 1 infection
…, J McCone Jr, BR Bacon, S Bruno… - … England Journal of …, 2011 - Mass Medical Soc
Background Peginterferon–ribavirin therapy is the current standard of care for chronic infection
with hepatitis C virus (HCV). The rate of sustained virologic response has been below 50…
with hepatitis C virus (HCV). The rate of sustained virologic response has been below 50…
The Simons Observatory: science goals and forecasts
The Simons Observatory (SO) is a new cosmic microwave background experiment being
built on Cerro Toco in Chile, due to begin observations in the early 2020s. We describe the …
built on Cerro Toco in Chile, due to begin observations in the early 2020s. We describe the …
Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial
Background Non-alcoholic steatohepatitis (NASH) is a common type of chronic liver disease
that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown …
that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown …
Mesenchymal stem cell-derived microvesicles protect against acute tubular injury
S Bruno, C Grange, MC Deregibus… - Journal of the …, 2009 - journals.lww.com
Administration of mesenchymal stem cells (MSCs) improves the recovery from acute kidney
injury (AKI). The mechanism may involve paracrine factors promoting proliferation of …
injury (AKI). The mechanism may involve paracrine factors promoting proliferation of …
The Atacama Cosmology Telescope: DR4 maps and cosmological parameters
… H 0 =67.6± 1.1 km/s/Mpc, at 68% confidence, in excellent agreement with the
independently-measured Planck satellite estimate (from ACT alone we find H 0 =67.9± 1.5 …
independently-measured Planck satellite estimate (from ACT alone we find H 0 =67.9± 1.5 …
[HTML][HTML] Preventing microalbuminuria in type 2 diabetes
P Ruggenenti, A Fassi, AP Ilieva, S Bruno… - … England Journal of …, 2004 - Mass Medical Soc
Background The multicenter double-blind, randomized Bergamo Nephrologic Diabetes
Complications Trial (BENEDICT) was designed to assess whether angiotensin-converting–…
Complications Trial (BENEDICT) was designed to assess whether angiotensin-converting–…